Western Blot Positive WB detected in: A549 whole cell lysate All lanes: PODXL antibody at 2.6microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 59, 56 kDa Observed band size: 59 kDa

PODXL Antibody

Name: PODXL Antibody
SKU: CSB-PA13447A0RB_C90
Availability: BackOrder

CSB-PA13447A0RB

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetPODXL

Overview

Supplier
Cusabio
Product Name
PODXL Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID5420
Target name
PODXL
Target description
podocalyxin like
Target synonyms
GCTM-2 antigen; gp135; Gp200; PC; PCLP; PCLP-1; PDX; podocalyxin; podocalyxin-like protein 1; PODXL1
Host
Rabbit
Isotype
IgG
Protein IDO00592
Protein Name
Podocalyxin
Scientific Description
Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

PODXL Antibody

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Overview

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