POLR2G Antibody

Cusabio

POLR2G Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

POLR2G

RNA polymerase II subunit G

RPB19, RPB7, hRPB19, hsRPB7, DNA-directed RNA polymerase II subunit RPB7, DNA directed RNA polymerase II 19 kda polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19 kDa subunit, RNA polymerase II seventh subunit, RNA polymerase II subunit B7, polymerase (RNA) II (DNA directed) polypeptide G, polymerase (RNA) II subunit G

Rabbit

IgG

DNA-directed RNA polymerase II subunit RPB7

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.

Human

-20°C or -80°C

41116161