POLR3E Antibody, FITC conjugated

Cusabio

POLR3E Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

POLR3E

RNA polymerase III subunit E

C37, RPC5, SIN, DNA-directed RNA polymerase III subunit RPC5, DNA-directed RNA polymerase III 80 kDa polypeptide, RNA polymerase III 80 kDa subunit RPC5, RNA polymerase III subunit C5, polymerase (RNA) III (DNA directed) polypeptide E (80kD), polymerase (RNA) III subunit E

Rabbit

IgG

DNA-directed RNA polymerase III subunit RPC5

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Human

-20°C or -80°C

41116161