POLR3K Antibody

Cusabio

POLR3K Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

POLR3K

RNA polymerase III subunit K

C11, C11-RNP3, HLD21, My010, RPC10, RPC11, RPC12.5, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit K, DNA-directed RNA polymerases III 12.5 kDa polypeptide, RNA polymerase III 12.5 kDa subunit, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RNA polymerase III subunit CII, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa, polymerase (RNA) III subunit K

Rabbit

IgG

DNA-directed RNA polymerase III subunit RPC10

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Human

-20°C or -80°C

41116161