Polyinosinic-polycytidylic acid (sodium)

MedChem Express

Polyinosinic-polycytidylic acid (sodium) [42424-50-0]

9

42424-50-0

Research Use Only

99.0

(C10H13N4O8P)x.(C9H14N3O8P)x.xNa

Polyinosinic-polycytidylic acid (Poly(I:C)) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors ( RIG-I and MDA5 ). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis [1] [2] .

O[C@H]1[C@@H](O[C@H](COP(O)(O)=O)[C@H]1O)N2C3=C(C(NC=N3)=O)N=C2.O[C@H]4[C@H](N5C(N=C(N)C=C5)=O)O[C@H](COP(O)(O)=O)[C@H]4O.[x].[x].[Na].[x]

-20°C

12352200