POMHEX

AbMole BioScience

POMHEX

9

2004714-34-3

Chemical

Research Use Only

C17H30NO9P

423.4

POMHEX, a racemic mixture and a cell-permeable pivaloyloxymethyl (POM) proagent of HEX, is a potent, ENO2-specific inhibitor of enolase. POMHEX exhibits low-nanomolar potency against ENO1-deleted cells in vitro and is capable of eradicating ENO1-deleted xenografted tumours in vivo. POMHEX is a potent glycolysis inhibitor.

CC(C)(C)C(=O)OCO[P](=O)(OCOC(=O)C(C)(C)C)C1CCCN(O)C1=O

12352200