Ponatinib

MedChem Express

Ponatinib [943319-70-8]

10

943319-70-8

Research Use Only

99.67

C29H27F3N6O

532.56

Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRalpha, VEGFR2, FGFR1, and Src, respectively[1].

CC1=C(C=C(C=C1)C(NC2=CC(C(F)(F)F)=C(C=C2)CN3CCN(CC3)C)=O)C#CC4=CN=C5N4N=CC=C5

-20°C,2°C to 8°C

12352200