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Ponatinib (hydrochloride)

HY-108766
MedChem Express
CAS Number1114544-31-8
Product group Chemicals
Estimated Purity99.55
Molecular Weight569.02
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ponatinib (hydrochloride) [1114544-31-8]
  • Delivery Days Customer
    10
  • CAS Number
    1114544-31-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.55
  • Molecular Formula
    C29H28ClF3N6O
  • Molecular Weight
    569.02
  • Scientific Description
    Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRalpha , VEGFR2 , FGFR1 , and Src , respectively [1] .
  • SMILES
    O=C(C1=CC=C(C)C(C#CC2=CN=C3C=CC=NN23)=C1)NC4=CC=C(CN5CCN(CC5)C)C(C(F)(F)F)=C4.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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