Ponatinib (hydrochloride)

MedChem Express

Ponatinib (hydrochloride) [1114544-31-8]

10

1114544-31-8

Research Use Only

99.55

C29H28ClF3N6O

569.02

Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRalpha , VEGFR2 , FGFR1 , and Src , respectively [1] .

O=C(C1=CC=C(C)C(C#CC2=CN=C3C=CC=NN23)=C1)NC4=CC=C(CN5CCN(CC5)C)C(C(F)(F)F)=C4.Cl

2°C to 8°C

12352200