Ponesimod-d4
HY-10569S
Molecular Weight465.00
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamePonesimod-d4
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC23H21D4ClN2O4S
- Molecular Weight465.00
- Scientific DescriptionPonesimod-d4 (ACT-128800-d4) is the deuterium labeled Ponesimod (HY-10569)[1]. Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation[2][3][4].
- SMILESO=C1N(C2=C([2H])C([2H])=C([2H])C([2H])=C2C)/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC
- UNSPSC12352200