Ponesimod-d7

MedChem Express

Ponesimod-d7

14

Research Use Only

96.50

C23H18D7ClN2O4S

468.02

Ponesimod-d 7 (ACT-128800-d 7 ) is the deuterium-labeled Ponesimod (HY-10569). Ponesimod-d 7 (ACT-128800) is a potent, selective and orally active agonist of S1P 1 , with an IC 50 of 6 nM in a radioligand binding assay. Ponesimod-d 7 activates S1P 1 -mediated signal transduction with high potency ( EC 50 =5.7 nM). Ponesimod-d 7 can protect against lymphocyte-mediated tissue inflammation [1] [2] [3] .

O=C1N(C2=C([2H])C([2H])=C([2H])C([2H])=C2C([2H])([2H])[2H])/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC

-20°C,2°C to 8°C

12352200