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WB analysis of EL4 cell lysate using GTX85223 PPAPDC1B antibody. Working concentration : (A) 1 and (B) 2 microg/ml
WB analysis of EL4 cell lysate using GTX85223 PPAPDC1B antibody. Working concentration : (A) 1 and (B) 2 microg/ml
WB analysis of EL4 cell lysate using GTX85223 PPAPDC1B antibody. Working concentration : (A) 1 and (B) 2 microg/ml

PPAPDC1B antibody

GTX85223
GeneTex
ApplicationsWestern Blot, ELISA
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetPLPP5
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Overview

  • Supplier
    GeneTex
  • Product Name
    PPAPDC1B antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1 - 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID84513
  • Target name
    PLPP5
  • Target description
    phospholipid phosphatase 5
  • Target synonyms
    diacylglycerol pyrophosphate like 1; diacylglycerol pyrophosphate phosphatase-like 1; DPPL1; HTPAP; phosphatidate phosphatase PPAPDC1B; phosphatidic acid phosphatase type 2 domain containing 1B; phosphatidic acid phosphatase type 2 domain-containing protein 1B; phospholipid phosphatase 5; PPAPDC1B; testicular secretory protein Li 38
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8NEB5
  • Protein Name
    Phospholipid phosphatase 5
  • Scientific Description
    Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203