PPAPDC2 antibody

GeneTex

PPAPDC2 antibody

9

WB: 1 microg/mL. ICC/IF: 20 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

PLPP6

phospholipid phosphatase 6

LPRP-B, PA-PSP, PDP1, PPAPDC2, PSDP, bA6J24.6, polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6, PPAP2 domain-containing protein 2, lipid phosphatase-related protein-B, phosphatidic acid phosphatase type 2 domain containing 2, phosphatidic acid phosphatase type 2 domain-containing protein 2, polyisoprenoid diphosphate phosphatase type 1, presqualene diphosphate phosphatase, type 1 polyisoprenoid diphosphate phosphatase

Rabbit

IgG

Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.

-20°C or -80°C,2°C to 8°C

12352203