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PPARdelta agonist 9 [928023-21-6]

HY-149429
MedChem Express
CAS Number928023-21-6
Product group Chemicals
Molecular Weight569.04
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PPARdelta agonist 9 [928023-21-6]
  • Delivery Days Customer
    14
  • CAS Number
    928023-21-6
  • Certification
    Research Use Only
  • Molecular Formula
    C26H28ClF3N4O3S
  • Molecular Weight
    569.04
  • Scientific Description
    PPARdelta agonist 9 (compound 21) is a PPARdelta agonist (EC50: 3.6 nM). PPARdelta agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%)[1].
  • SMILES
    ClC1=CC(CC(O)=O)=CC(OCCC2(N3CCCC3)CCN(C4=NC5=CC=C(N=C5S4)C(F)(F)F)CC2)=C1
  • UNSPSC
    12131703