PPARgamma phosphorylation inhibitor 1

MedChem Express

PPARgamma phosphorylation inhibitor 1 [2882975-84-8]

10

Research Use Only

99.81

C22H14Cl2N2O4

441.26

PPARgamma phosphorylation inhibitor 1 (Compound 10) is a potent PPARgamma binder with the IC50 of 24 nM. PPARgamma phosphorylation inhibitor 1 inhibits CDK5-mediated phosphorylation of PPARgamma Ser273 with the IC50 of 160 nM. PPARgamma phosphorylation inhibitor 1 displays negligible PPARgamma agonism in a reporter gene assay. Antidiabetic effects[1].

O=C(C1=NN(C(C2=C1C=CC(OC3=CC=CC=C3)=C2)=O)CC4=CC(Cl)=C(C=C4)Cl)O

-20°C,2°C to 8°C

12131703