PPARgamma/delta modulator 1

MedChem Express

PPARgamma/delta modulator 1 [2089159-00-0]

10

Research Use Only

C18H18ClIN6O3Se

607.69

PPARgamma/delta modulator 1 (compound 3e) is a potent PPAR modulator. PPARgamma/delta modulator 1 is a PPARdelta antagonist and a PPARgamma partial agonist , with Ki values of 14.4 nM and 5.31 microM, respectively. PPARgamma/delta modulator 1 has the EC50 of 7.3 and 12.6 microM for PPARdelta corepression and adiponectin production, respectively[1].

O[C@H]1[C@H]([C@@H]([Se][C@@H]1C(NC)=O)N2C3=C(N=C2)C(NCC4=CC=CC(I)=C4)=NC(Cl)=N3)O

12131703