PPI-GIT1/beta-Pix PPI-IN-1

MedChem Express

PPI-GIT1/beta-Pix PPI-IN-1 [2070916-70-8]

5

Research Use Only

99.01

C23H21NO5

391.42

PPI-GIT1/beta-Pix interaction-IN-1 is a potent and orally active GIT1/beta-Pix protein-protein interaction (PPI) inhibitor with a KD value of 7.7 microM. PPI-GIT1/beta-Pix interaction-IN-1 disrupts the GIT/PIX interaction can impact the activation of the downstream Rho GTPase Rac1 and Cdc42. PPI-GIT1/beta-Pix interaction-IN-1 inhibits metastasis of gastric cancer[1].

O=C([C@@H]1[C@@H](C(OCC)=O)[C@]2(C(N(C)C3=C2C=CC=C3)=O)[C@H]/4C1)C4=C\C5=COC=C5

-20°C,2°C to 8°C

12131703