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PPM1M Polyclonal Antibody

RD219190A
Reddot Biotech
TargetPPM1M
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PPM1M Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    1.74 mg/ml
  • Gene ID132160
  • Target name
    PPM1M
  • Target description
    protein phosphatase, Mg2+/Mn2+ dependent 1M
  • Target synonyms
    PP2CE; PP2Ceta; PP2C-eta; protein phosphatase 1M; protein phosphatase 1M (PP2C domain containing); protein phosphatase 2C eta-2
  • Scientific Description
    PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203