PPP2R1A antibody
GTX102206
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPPP2R1A
Overview
- SupplierGeneTex
- Product NamePPP2R1A antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:2500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.12 mg/ml
- ConjugateUnconjugated
- Gene ID5518
- Target namePPP2R1A
- Target descriptionprotein phosphatase 2 scaffold subunit Aalpha
- Target synonymsmedium tumor antigen-associated 61 KDA protein; MRD36; PP2AA; PP2AAALPHA; PP2A-Aalpha; PR65A; protein phosphatase 2, regulatory subunit A, alpha; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; testicular secretory protein Li 1
- HostRabbit
- IsotypeIgG
- Protein IDP30153
- Protein NameSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- Scientific DescriptionThis gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Protein phosphatase 2A inactivation induces microsatellite instability, neoantigen production and immune response. Yen YT et al., 2021 Dec 15, Nat CommunRead more
- PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Yen YT et al., 2021 Jun 2, Commun BiolRead more
- PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo. Yen YT et al., 2019 Dec 30, CellsRead more
- Neuronal ceroid lipofuscinosis related ER membrane protein CLN8 regulates PP2A activity and ceramide levels. Adhikari B et al., 2019 Feb 1, Biochim Biophys Acta Mol Basis DisRead more
- Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress. Martina JA et al., 2018 Aug 10, J Biol ChemRead more
- Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Tsao HW et al., 2013 Sep 24, Proc Natl Acad Sci U S ARead more
- The Royal Australasian College of Physicians Golden Jubilee meeting. Sydney, 8-13 May 1988. Proceedings of meetings of special societies and colleges. Abstracts., 1988 May, Aust N Z J MedRead more