ProductsBack/PPP2R2D antibody [N2C3]

PPP2R2D antibody [N2C3]

Name: PPP2R2D antibody [N2C3]
SKU: GTX116609_G10
Availability: BackOrder

GTX116609

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetPPP2R2D

Overview

Supplier
GeneTex
Product Name
PPP2R2D antibody [N2C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.5 mg/ml
Conjugate
Unconjugated
Gene ID55844
Target name
PPP2R2D
Target description
protein phosphatase 2 regulatory subunit Bdelta
Target synonyms
B55D, B55delta, MDS026, serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform, protein phosphatase 2 regulatory subunit B, delta
Host
Rabbit
Isotype
IgG
Protein IDQ66LE6
Protein Name
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Scientific Description
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Kim YS, Ko B, Kim DJ, et al. Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D. Nat Commun. 2022,13(1):6080. doi: 10.1038/s41467-022-33749-0
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Álvarez-Fernández M, Sanz-Flores M, Sanz-Castillo B, et al. Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer. Cell Death Differ. 2018,25(5):828-840. doi: 10.1038/s41418-017-0024-0
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Joseph BK, Liu HY, Francisco J, et al. Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d. J Biol Chem. 2015,290(17):10588-98. doi: 10.1074/jbc.M114.626259
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Kurimchak A, Haines DS, Garriga J, et al. Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme. Mol Cell Biol. 2013,33(16):3330-42. doi: 10.1128/MCB.00082-13
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