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PPP2R2D antibody [N2C3]

GTX116609
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPP2R2D
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Overview

  • Supplier
    GeneTex
  • Product Name
    PPP2R2D antibody [N2C3]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Based on sequence homology, this antibody may cross react with other PPP2R2A, PPP2R2B, and PPP2R2C family members.
  • Application Supplier Note
    WB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID55844
  • Target name
    PPP2R2D
  • Target description
    protein phosphatase 2 regulatory subunit Bdelta
  • Target synonyms
    B55D; B55delta; MDS026; protein phosphatase 2 regulatory subunit B, delta; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ66LE6
  • Protein Name
    Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
  • Scientific Description
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D. Kim YS et al., 2022 Oct 14, Nat Commun
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  • Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer. alvarez-Fernandez M et al., 2018 May, Cell Death Differ
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  • Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d. Joseph BK et al., 2015 Apr 24, J Biol Chem
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  • Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55alpha holoenzyme. Kurimchak A et al., 2013 Aug, Mol Cell Biol
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