PPP4R2 antibody
GTX121559
Overview
- SupplierGeneTex
- Product NamePPP4R2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID151987
- Target namePPP4R2
- Target descriptionprotein phosphatase 4 regulatory subunit 2
- Target synonymsPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
- HostRabbit
- IsotypeIgG
- Protein IDQ9NY27
- Protein NameSerine/threonine-protein phosphatase 4 regulatory subunit 2
- Scientific DescriptionRegulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203