PptT-IN-1

MedChem Express

PptT-IN-1

10

Research Use Only

C18H29N5O2

347.46

PptT-IN-1 (compound 5j) is a potent inhibitor of with phosphopantetheinyl phosphoryl transferase (PptT) an IC50 of 2.8 microM. Phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. PptT-IN-1 has the potential for the research of tuberculosis[1].

CCNC(NC(NC1=C(C=C(C=C1CC)C(NC(C)C)=O)CC)=O)=N

12352200