PptT-IN-2

MedChem Express

PptT-IN-2

10

Research Use Only

C22H29N5O2

395.50

PptT-IN-2 (compound 5k) is a potent inhibitor of with phosphopantetheinyl phosphoryl transferase (PptT) an IC50 of 2.5 microM. Phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. PptT-IN-2 has the potential for the research of tuberculosis[1].

CCNC(NC(NC1=C(C=C(C=C1CC)C(NCC2=CC=CC=C2)=O)CC)=O)=N

12352200