More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/PQ401 [196868-63-0]

PQ401 [196868-63-0]

Research Use Only
HY-13686
MedChem Express
CAS Number196868-63-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.85
Molecular Weight341.79
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    PQ401 [196868-63-0]
  • Delivery Days Customer
    10
  • CAS Number
    196868-63-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.85
  • Molecular Formula
    C18H16ClN3O2
  • Molecular Weight
    341.79
  • Scientific Description
    PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 microM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 microM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis[1].
  • SMILES
    O=C(NC1=CC(C)=NC2=CC=CC=C12)NC3=C(OC)C=CC(Cl)=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200