PQBP1 Antibody

Cusabio

PQBP1 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

PQBP1

polyglutamine binding protein 1

38 kDa nuclear protein containing a WW domain; MRX2; MRX55; MRXS3; MRXS8; NPW38; polyglutamine tract-binding protein 1; polyglutamine-binding protein 1; RENS1; SHS

Rabbit

IgG

Polyglutamine-binding protein 1

Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

-20°C or -80°C

12352203