Pradefovir [625095-60-5]

MedChem Express

Pradefovir [625095-60-5]

5

625095-60-5

Research Use Only

C17H19ClN5O4P

423.79

Pradefovir is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 microM.

NC1=C2N=CN(CCOC[P@]3(OCC[C@@H](C4=CC=CC(Cl)=C4)O3)=O)C2=NC=N1

12352200