IHC-P analysis of human liver carcinoma (A), esophagus carcinoma (B), normal spleen tissue(C), breast carcinoma (D) using GTX83275 PRAK antibody [7H10B4].
![WB analysis of truncated PRAK recombinant protein using GTX83275 PRAK antibody [7H10B4].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83275/GTX83275_20170912_WB_w_23061322_966.webp "WB analysis of truncated PRAK recombinant protein using GTX83275 PRAK antibody [7H10B4].")
IHC-P analysis of human liver carcinoma (A), esophagus carcinoma (B), normal spleen tissue(C), breast carcinoma (D) using GTX83275 PRAK antibody [7H10B4].
PRAK antibody [7H10B4]
GTX83275
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMAPKAPK5
Overview
- SupplierGeneTex
- Product NamePRAK antibody [7H10B4]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID7H10B4
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID8550
- Target nameMAPKAPK5
- Target descriptionMAPK activated protein kinase 5
- Target synonymsMAP kinase-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
- HostMouse
- IsotypeIgG1
- Protein IDQ8IW41
- Protein NameMAP kinase-activated protein kinase 5
- Scientific DescriptionThe protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203