Pralatrexate [146464-95-1]
HY-10446
Overview
- SupplierMedChem Express
- Product NamePralatrexate [146464-95-1]
- Delivery Days Customer10
- CAS Number146464-95-1
- CertificationResearch Use Only
- Estimated Purity95%
- Molecular FormulaC23H23N7O5
- Molecular Weight477.47
- Scientific DescriptionPralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor with a Ki of 13.4 pM. Pralatrexate is a substrate for folylpolyglutamate synthetase with improved cellular uptake and retention. Pralatrexate has antitumor activities and has the potential for relapsed/refractory T-cell lymphoma treatment.
- SMILESO=C(CC[C@H](NC(C1=CC=C(C=C1)C(CC#C)CC2=NC3=C(N=C(N=C3N=C2)N)N)=O)C(O)=O)O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200