Pralsetinib

MedChem Express

Pralsetinib [2097132-94-8]

10

2097132-94-8

Research Use Only

99.98

C27H32FN9O2

533.60

Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC 50 s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively [1] .

O=C([C@@]1(OC)CC[C@H](C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)CC1)N[C@H](C4=CC=C(N5N=CC(F)=C5)N=C4)C

-20°C,2°C to 8°C

12352200