
Chemical Structure
Pravastatin sodium salt hydrate [81131-70-6]

CDX-P0933
CAS Number81131-70-6
Product group Chemicals
Overview
- SupplierChemodex
- Product NamePravastatin sodium salt hydrate [81131-70-6]
- Delivery Days Customer10
- CAS Number81131-70-6
- CertificationResearch Use Only
- Scientific DescriptionChemical. CAS: 81131-70-6 (sodium salt) - 81093-37-0 (free acid). Formula: C23H35O7Na. MW: BD9837. Pravastatin is a water-soluble, orally effective, competitive inhibitor of Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (Ki = 2.3nM), the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering/regulating compounds. Pravastatin potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. Pravastatin reduces LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Pravastatin also acts as an immunomodulator and as an inhibitor of p21ras isoprenylation. - Pravastatin is a water-soluble, orally effective, competitive inhibitor of Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (Ki = 2.3nM), the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering/regulating compounds. Pravastatin potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. Pravastatin reduces LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Pravastatin also acts as an immunomodulator and as an inhibitor of p21ras isoprenylation.
- Storage Instruction2°C to 8°C,RT
- UNSPSC12352200