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Chemical Structure
Chemical Structure
Chemical Structure

Pravastatin sodium salt hydrate [81131-70-6]

Research Use Only
CDX-P0933
Chemodex
CAS Number81131-70-6
Product group Chemicals
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Overview

  • Supplier
    Chemodex
  • Product Name
    Pravastatin sodium salt hydrate [81131-70-6]
  • Delivery Days Customer
    10
  • CAS Number
    81131-70-6
  • Certification
    Research Use Only
  • Scientific Description
    Chemical. CAS: 81131-70-6 (sodium salt) - 81093-37-0 (free acid). Formula: C23H35O7Na. MW: BD9837. Pravastatin is a water-soluble, orally effective, competitive inhibitor of Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (Ki = 2.3nM), the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering/regulating compounds. Pravastatin potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. Pravastatin reduces LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Pravastatin also acts as an immunomodulator and as an inhibitor of p21ras isoprenylation. - Pravastatin is a water-soluble, orally effective, competitive inhibitor of Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (Ki = 2.3nM), the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering/regulating compounds. Pravastatin potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. Pravastatin reduces LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Pravastatin also acts as an immunomodulator and as an inhibitor of p21ras isoprenylation.
  • Storage Instruction
    2°C to 8°C,RT
  • UNSPSC
    12352200