Prazobind-d8 [1189701-23-2]

MedChem Express

Prazobind-d8 [1189701-23-2]

999

1189701-23-2

Research Use Only

C23H19D8N5O3

429.54

Prazobind-d8 is the deuterium labeled Prazobind (HY-118335). Prazobind (SZL 49), a prazosin analog, is a selective alpha1-adrenoceptor antagonist. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50 of 1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes. Prazobind can be used for the study of blood pressure[1][2].

NC1=NC(N2C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C2([2H])[2H])C(C3=CC4CCC3C=C4)=O)=NC5=C1C=C(OC)C(OC)=C5

12352200