IHC-P analysis of human brain tissue using GTX03275 PRDM16 antibody. Dilution : 20 microg/ml
IHC-P analysis of human brain tissue using GTX03275 PRDM16 antibody. Dilution : 20 microg/ml
PRDM16 antibody
GTX03275
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPRDM16
Overview
- SupplierGeneTex
- Product NamePRDM16 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID63976
- Target namePRDM16
- Target descriptionPR/SET domain 16
- Target synonymsCMD1LL; histone-lysine N-methyltransferase PRDM16; KMT8F; LVNC8; MDS1/EVI1-like gene 1; MEL1; PFM13; PR domain 16; PR domain containing 16; PR domain zinc finger protein 16; transcription factor MEL1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203