Prealbumin [87090-18-4]
16-16-161801
Protein IDP02766
Product group Proteins / Signaling Molecules
Overview
- SupplierAthens Research
- Product NamePrealbumin [87090-18-4]
- Delivery Days Customer9
- Applications SupplierInflammation, In Vitro Diagnostics, Cardiovascular
- CertificationResearch Use Only
- Estimated Purity≥95% by SDS-PAGE.
- Protein IDP02766
- Protein NameTransthyretin
- Scientific DescriptionPrealbumin, also known as transthyretin, is a serum protein present in plasma at approximately 30 mg per 100 ml. Synthesized primarily in the liver, prealbumin plays a vital role in transporting thyroxine (T4), vitamin A, and retinol-binding protein throughout the bloodstream. Its structure allows it to form complexes with these molecules, facilitating their delivery to target tissues. Prealbumin has a short biological half-life of about two days, making it a sensitive marker for acute changes in nutritional status and protein-energy malnutrition. Clinically, low prealbumin levels are commonly observed in conditions such as viral hepatitis, cirrhosis, malnutrition, inflammation, acute kidney injury, and after surgical trauma. Decreased levels are associated with poor prognosis and increased mortality in critically ill and hospitalized patients. Prealbumin measurement is widely used to monitor nutritional interventions, assess liver function, and predict patient outcomes, especially in acute and chronic disease management.
- Shelf life instructionmore then 1 year
- SourceSource human plasma non-reactive for HBsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
- Storage Instruction≤ -20°C
- UNSPSC12352202
References
- Iino, T., et al., (2024), 'Assessment of transthyretin instability in patients with wild‑type transthyretin amyloid cardiomyopathy', Scientific Reports. 14: pp 20508.Read this paper
- Zheng, Y. Z., et al., (2017), 'Manipulating trypsin digestion conditions to accelerate proteolysis and simplify digestion workflows in development of protein mass spectrometric assays for the clinical laboratory', Clinical Mass Spectrometry 6: pp 1–12Read this paper