Pregnenolone

MedChem Express

Pregnenolone [145-13-1]

10

145-13-1

Research Use Only

99.87

C21H32O2

316.48

Pregnenolone (3beta-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor , inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors . Pregnenolone can protect the brain from cannabis intoxication [1] [2] . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels [3] .

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-20°C,2°C to 8°C

12352200