Pregnenolone 16alpha-carbonitrile

MedChem Express

Pregnenolone 16alpha-carbonitrile [1434-54-4]

10

1434-54-4

Research Use Only

98.48

C22H31NO2

341.49

Pregnenolone 16alpha-carbonitrile is an orally active prototypical and effective rodent-PXR activator. Pregnenolone 16alpha-carbonitrile, a synthetic steroid, induces cytochrome P450 3A expression. Pregnenolone 16alpha-carbonitrile exhibits increased resistance to subsequent stressful insults [1] [2] [3] .

C[C@@]12[C@](C[C@H]([C@@H]2C(C)=O)C#N)([H])[C@@]3([H])[C@]([C@@]4(C(C[C@H](CC4)O)=CC3)C)([H])CC1

-20°C

12352200