Pretomanid

MedChem Express

Pretomanid [187235-37-6]

10

187235-37-6

Research Use Only

99.97

C14H12F3N3O5

359.26

Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 microg/mL.

FC(F)(F)OC(C=C1)=CC=C1CO[C@@H]2COC3=NC([N+]([O-])=O)=CN3C2

-20°C,2°C to 8°C

12352200