Prexasertib (Mesylate Hydrate) [1234015-57-6]
HY-18174B
CAS Number1234015-57-6
Product group Chemicals
Molecular Weight479.51
Overview
- SupplierMedChem Express
- Product NamePrexasertib (Mesylate Hydrate) [1234015-57-6]
- Delivery Days Customer10
- CAS Number1234015-57-6
- CertificationResearch Use Only
- Molecular FormulaC19H25N7O6S
- Molecular Weight479.51
- Scientific DescriptionPrexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib Mesylate Hydrate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib Mesylate Hydrate shows potent anti-tumor activity[1][2].
- SMILESN#CC1=NC=C(NC2=NNC(C3=C(OC)C=CC=C3OCCCN)=C2)N=C1.CS(=O)(O)=O.O
- UNSPSC12352200