Immunofluorescence staining of HepG2 cells with CSB-PA018668LA01MO at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunofluorescence staining of HepG2 cells with CSB-PA018668LA01MO at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Prf1 Antibody
CSB-PA018668LA01MO
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityMouse
TargetPrf1
Overview
- SupplierCusabio
- Product NamePrf1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID18646
- Target namePrf1
- Target descriptionperforin 1 (pore forming protein)
- Target synonymsPfn, Pfp, Prf-1, perforin-1, P1, cytolysin, lymphocyte pore-forming protein, pore forming protein
- HostRabbit
- IsotypeIgG
- Protein IDP10820
- Protein NamePerforin-1
- Scientific DescriptionPlays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
- ReactivityMouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
Related products
Product group Antibodies
References
Perforin antibody [CB5.4]GTX16074
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetPrf1
- SizePrice
