Prinomastat (hydrochloride)

MedChem Express

Prinomastat (hydrochloride) [1435779-45-5]

10

1435779-45-5

Research Use Only

98.18

C18H22ClN3O5S2

459.97

Prinomastat hydrochloride (AG3340 hydrochloride) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC 50 s of 79, 6.3 and 5.0 nM for MMP-1 , MMP-3 and MMP-9 , respectively. Prinomastat hydrochloride inhibits MMP-2 , MMP-3 , MMP-13 and MMP-9 with K i s of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat hydrochloride can cross blood-brain barrier. Antitumor avtivity [1] [2] [3] [4] .

O=C([C@@H]1N(S(=O)(C2=CC=C(OC3=CC=NC=C3)C=C2)=O)CCSC1(C)C)NO.[H]Cl

2°C to 8°C

12352200