proBNP antibody [24E11]

GeneTex

proBNP antibody [24E11]

9

NT-proBNP and proBNP

Western Blot, ELISA

Research Use Only

Monoclonal

Unconjugated

NPPB

natriuretic peptide B

BNP; brain natriuretic factor prohormone; brain type natriuretic peptide; gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; natriuretic peptides B; natriuretic protein; preproBNP; proBNP

Mouse

IgG2a

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The proteins biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

Human

2°C to 8°C

12352203