Procarbazine hydrochloride [366-70-1]

TargetMol Chemicals

Procarbazine hydrochloride

4

366-70-1

Chemical

Research Use Only

Procarbazine hydrochloride

98%

C12H19N3O HCl

257.76

Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated, procarbazine, after metabolic activation, appears to inhibit the trans-methylation of methionine into transfer RNA (t-RNA), thereby preventing protein synthesis and consequently DNA and RNA synthesis. This agent may also undergo auto-oxidation, resulting in the formation of cytotoxic free radicals which damage DNA through an alkylation reaction.

3 years

c1(C(=O)NC(C)C)ccc(cc1)CNNC.Cl

-20°C

12352200