
IHC-P analysis of human intestine tissue using GTX47135 PRODH2 antibody at 4.0-8.0microg/ml.
PRODH2 antibody, C-term
GTX47135
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPRODH2
Overview
- SupplierGeneTex
- Product NamePRODH2 antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID58510
- Target namePRODH2
- Target descriptionproline dehydrogenase 2
- Target synonymsHSPOX1; hydroxyproline dehydrogenase; HYPDH; kidney and liver proline oxidase 1; probable proline dehydrogenase 2; probable proline oxidase 2; proline dehydrogenase (oxidase) 2
- HostRabbit
- IsotypeIgG
- Protein IDQ9UF12
- Protein NameHydroxyproline dehydrogenase
- Scientific DescriptionThe protein encoded by this gene catalyzes the first step in the catabolism of trans-4-hydroxy-L-proline, an amino acid derivative obtained through food intake and collagen turnover. One of the downstream products of this catabolism is glyoxylate, which in people with disorders of glyoxalate metabolism can lead to an increase in oxalate levels and the formation of calcium-oxalate kidney stones. Therefore, this gene may serve as a therapeutic target against primary hyperoxalurias (PH). This gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme that catalyzes the first step in proline catabolism. [provided by RefSeq, Jan 2017]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203