Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
TMPY-03269
Product group Molecular Biology
Overview
- SupplierTargetMol Chemicals
- Product NameProlyl Endopeptidase Protein, Mouse, Recombinant (His)
- Delivery Days Customer16
- CertificationResearch Use Only
- Scientific DescriptionProlyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotensin, neurotensin, oxytocin, substance P and vasopressin. Prolyl endopeptidases activity is confined to action on oligopeptides of less than 10 kD and it has an absolute requirement for the trans-configuration of the peptide bond preceding proline. It cleaves peptide bonds at the C-terminal side of proline residues.
- Storage Instruction-20°C
- UNSPSC12352204