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ProductsBack/Propafenone hydrochloride

Propafenone hydrochloride

M3412

CAS Number34183-22-7

Product group Chemicals

Molecular Weight377.9

Overview

Supplier
AbMole BioScience
Product Name
Propafenone hydrochloride
Delivery Days Customer
9
CAS Number
34183-22-7
Certification
Research Use Only
Molecular Formula
C21H27NO3.HCl
Molecular Weight
377.9
Scientific Description
Propafenone HCl is a sodium-channel blocker that also has a high affinity for bèta-receptors (IC50 = 32 nM). It blocks transient outward potassium current (Ito) and sustained delayed rectifier K+ current (Isus) with IC50 values of 4.9 uM and 8.6 uM, respectively.In addition, Propafenone inhibits the proliferation of esophageal cancer by inducing mitochondrial dysfunction and apoptosis.
SMILES
CCCNCC(O)COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2
UNSPSC
12352200

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