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Propafenone hydrochloride

M3412
AbMole BioScience
CAS Number34183-22-7
Product group Chemicals
Molecular Weight377.9
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Propafenone hydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    34183-22-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C21H27NO3.HCl
  • Molecular Weight
    377.9
  • Scientific Description
    Propafenone HCl is a sodium-channel blocker that also has a high affinity for bèta-receptors (IC50 = 32 nM). It blocks transient outward potassium current (Ito) and sustained delayed rectifier K+ current (Isus) with IC50 values of 4.9 uM and 8.6 uM, respectively.In addition, Propafenone inhibits the proliferation of esophageal cancer by inducing mitochondrial dysfunction and apoptosis.
  • SMILES
    CCCNCC(O)COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2
  • UNSPSC
    12352200

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