Propargyl-PEG1-acid [55683-37-9]
HY-130504
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NamePropargyl-PEG1-acid [55683-37-9]
- Delivery Days Customer5
- CAS Number55683-37-9
- CertificationResearch Use Only
- Estimated Purity97.0
- Molecular FormulaC6H8O3
- Molecular Weight128.13
- Scientific DescriptionPropargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs Ibrutinib(HY-10997)-based PROTAC 4 and PROTAC 5. PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 microM[1]. Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO=C(O)CCOCC#C
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41115800