ProductsBack/Propoxur-d3 [1219798-56-7]

Propoxur-d3 [1219798-56-7]

Name: Propoxur-d3 [1219798-56-7]
SKU: HY-B0916S_M09
Availability: BackOrder

HY-B0916S

CAS Number1219798-56-7

Product group Chemicals

Molecular Weight212.26

Overview

Supplier
MedChem Express
Product Name
Propoxur-d3 [1219798-56-7]
Delivery Days Customer
5
CAS Number
1219798-56-7
Category Supplier
CHEMICAL,detergents_surfactants
Certification
Research Use Only
Molecular Formula
C11H12D3NO3
Molecular Weight
212.26
Scientific Description
Propoxur-d3 is the deuterated form of Propoxur (HY-B0916). Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests[1][2][3][4].
SMILES
O=C(NC([2H])([2H])[2H])OC1=C(OC(C)C)C=CC=C1
UNSPSC
12352005