Prosapip1 antibody

GeneTex

Prosapip1 antibody

9

WB: 1 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

LZTS3

leucine zipper tumor suppressor family member 3

leucine zipper putative tumor suppressor 3; leucine zipper, putative tumor suppressor family member 3; proline rich synapse associated protein interacting protein 1; ProSAP/Shank-interacting protein 1; PROSAPIP1

Rabbit

IgG

Leucine zipper putative tumor suppressor 3

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3s PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed Fezzins. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203