PROTAC BET Degrader-10 [1957234-97-7]

MedChem Express

PROTAC BET Degrader-10 [1957234-97-7]

9

1957234-97-7

Research Use Only

99.39

C39H39ClN8O6S

783.29

PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4, with a DC50 of 49 nM[1].

O=C(NCCCCCC(NCC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4

-20°C,2°C to 8°C

12352200