PROTAC BET degrader-2

Biorbyt

PROTAC BET degrader-2

16

2093388-33-9

Research Use Only

C41H42N10O6

770.84

PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression.

O=C(C1=NC(NC2=CC(C3CC3)=NN2CC)=C4C(NC5=C4C=C(OC)C(C6=C(C)ON=C6C)=C5)=N1)NCCCC7=CC=CC8=C7CN(C(CC9)C(NC9=O)=O)C8=O

12352200