PROTAC BRD3/BRD4-L degrader-2

MedChem Express

PROTAC BRD3/BRD4-L degrader-2

10

Research Use Only

C43H44ClN7O3

742.31

PROTAC BRD3/BRD4-L degrader-2 is a PROTAC molecule and can selectively degrade cellular BRD3 and BRD4-L with Ki values of 16.91 and 2.8 nM, respectively. PROTAC BRD3/BRD4-L degrader-2 also has robust antitumor activity in mouse xenograft models. PROTAC BRD3/BRD4-L degrader-2 can be used for the research of cancer.

CC1=NN=C2CCC(C3=C(N12)C=CC(C4=CC=C(C=C4)CN(C)CCCCC5=C6CN(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=C3)NC8=CC=C(C=C8)Cl

See Manual

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