PROTAC BTK Degrader-1 [2801715-13-7]
HY-147943
CAS Number2801715-13-7
Product group Chemicals
Estimated Purity98.87
Molecular Weight749.86
Overview
- SupplierMedChem Express
- Product NamePROTAC BTK Degrader-1 [2801715-13-7]
- Delivery Days Customer10
- CAS Number2801715-13-7
- CertificationResearch Use Only
- Estimated Purity98.87
- Molecular FormulaC43H43N9O4
- Molecular Weight749.86
- Scientific DescriptionPROTAC BTK Degrader-1 is a potent, selective and orally active PROTAC BTK degrader with an IC50 value of 34.51 nM and 64.56 nM for BTK WT and BTK-481S, respectively. PROTAC BTK Degrader-1 effectively reduces BTK protein levels and suppresses tumor growth[1]. PROTAC BTK Degrader-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO=C(N1)C(CCC1=O)N(C2=O)CC3=C2C=CC(C#CCN4CCC(CC4)N5CCC(CC5)N6N=C(C7=C(N=CN=C76)N)C8=CC=C(C=C8)OC9=CC=CC=C9)=C3
- Storage Instruction2°C to 8°C
- UNSPSC12131703